Methylparaben chemical structure
Also known as

Methyl 4-hydroxybenzoate

Methyl p-hydroxybenzoate

Methyl parahydroxybenzoate

Nipagin M

E number E218



Derived from

esterification is carried out with p-hydroxybenzoic acid in the presence of an alcohol (methanol)

TypeChemically derived

What is methylparaben used for?

Methylparaben is used as a fragrance ingredient, preservative / antimicrobial and antifungal agent in cosmetics including creams, lotions, and underarm deodorants.

Are there any health concerns when using methylparaben?

Methylparaben is a possible endocrine disruptor and possibly has reproductive toxicity. Some research shows patients with breast tumors have a build up of Methylparabens in the breast tissue.

Warnings from regulatory agencies regarding methylparaben

  1. Whole Foods Market Unacceptable Ingredients
  2. Oestrogenic activity of p-hydroxybenzoic acid (common metabolite of paraben esters) and methylparaben in human breast cancer cell lines
  3. Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells
  4. Human Semen Quality, Sperm DNA Damage, and the Level of Reproductive Hormones in Relation to Urinary Concentrations of Parabens

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